If we received some type of vague alien communication whose validity, meaning, and purpose we would struggle immensely to discern, I'm certain we would hardly bat an eye, much less make any dedicated, meaningful effort to establish any type of contact.

I would say the most likely outcome is that any message we send would fall on deaf hearing appendages, even though something exists which could receive it.

Edit: Also, consider the level of strife, conflict, and technological disparity amongst our own species. The odds of a message even being received and recognized for what it is seem slim.