I've had my nuvi 250 for over a year now. It's ugly but with pretty good build quality. I've dropped it many times and it still works fine. I should mention that I dropped it not out of clumsiness (except for once when it was raining and I slipped with it in my pocket), but because the rubber mount loses its grip on glass over time. It occasionally falls off under hard acceleration.
Other than that it works fine. I wouldn't give it any awards but it hasn't failed me yet and the maps are very accurate. Which is just what one needs in a GPS system.
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