Ive never played 1 or 2 either. There are a few things I think I missed out on, mainly relationships between characters, but there is all of that info in the game if you care to read it. You kinda just figure it out after playing for a little while though.

If you liked Skyrim, you'll like this.

Also, it is a DRM free game, which means you can DL it and test it out and if you like it, buy it. Thats what I did. I wish all games were like that. I hate spending $60 on a game and then realizing I dont like it.